Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection

S-adenosylmethionine (SAM) minimizes alcohol hepatotoxicity; however, the molecular mechanisms responsible for SAM hepatoprotection remain unknown. Herein, we use proteomics to determine whether the hepatoprotective action of SAM against early-stage alcoholic liver disease is linked to alterations i...

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Bibliographic Details
Main Authors: Andringa, Kelly K., King, Adrienne L., Eccleston, Heather B., Mantena, Sudheer K., Landar, Aimee, Jhala, Nirag C., Dickinson, Dale A., Squadrito, Giuseppe L., Bailey, Shannon M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
Subjects:
Liver and Biliary Tract
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867419/
https://ncbi.nlm.nih.gov/pubmed/20150243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00332.2009
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