Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair

To understand how multiprotein complexes assemble and function on chromatin, we combined quantitative analysis of the mammalian nucleotide excision DNA repair (NER) machinery in living cells with computational modeling. We found that individual NER components exchange within tens of seconds between...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Luijsterburg, Martijn S., von Bornstaedt, Gesa, Gourdin, Audrey M., Politi, Antonio Z., Moné, Martijn J., Warmerdam, Daniël O., Goedhart, Joachim, Vermeulen, Wim, van Driel, Roel, Höfer, Thomas
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2010
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867314/
https://ncbi.nlm.nih.gov/pubmed/20439997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909175
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