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Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair
To understand how multiprotein complexes assemble and function on chromatin, we combined quantitative analysis of the mammalian nucleotide excision DNA repair (NER) machinery in living cells with computational modeling. We found that individual NER components exchange within tens of seconds between...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867314/ https://ncbi.nlm.nih.gov/pubmed/20439997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909175 |
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