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Classical and/or alternative NF-κB pathway activation in multiple myeloma
Mutations involving the nuclear factor-κB (NF-κB) pathway are present in at least 17% of multiple myeloma (MM) tumors and 40% of MM cell lines (MMCLs). These mutations, which are apparent progression events, enable MM tumors to become less dependent on bone marrow signals that activate NF-κB. Studie...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867265/ https://ncbi.nlm.nih.gov/pubmed/20053756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-243535 |
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