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Mining protein dynamics from sets of crystal structures using “consensus structures”

In this work, we describe two novel approaches to utilize the dynamic structure information implicitly contained in large crystal structure data sets. The first approach visualizes both consistent as well as variable ligand-induced changes in ligand-bound compared with apo protein crystal structures...

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Bibliografiske detaljer
Main Authors: van Westen, Gerard J P, Wegner, Jörg K, Bender, Andreas, IJzerman, Adriaan P, van Vlijmen, Herman W T
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867014/
https://ncbi.nlm.nih.gov/pubmed/20120021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.350
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