Ozone activates pulmonary dendritic cells and promotes allergic sensitization by a TLR4-dependent mechanism

Human exposure to ozone is associated with increased prevalence of allergic asthma. Here, we demonstrate that ozone increases levels of activated dendritic cells in thoracic lymph nodes and promotes allergic sensitization through a TLR4-dependent pathway.

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Bibliographic Details
Main Authors: Hollingsworth, John W., Free, Meghan E., Li, Zhuowei, Andrews, Laura Novack, Nakano, Hideki, Cook, Donald N.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866779/
https://ncbi.nlm.nih.gov/pubmed/20394980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.03.001
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