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Ozone activates pulmonary dendritic cells and promotes allergic sensitization by a TLR4-dependent mechanism
Human exposure to ozone is associated with increased prevalence of allergic asthma. Here, we demonstrate that ozone increases levels of activated dendritic cells in thoracic lymph nodes and promotes allergic sensitization through a TLR4-dependent pathway.
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866779/ https://ncbi.nlm.nih.gov/pubmed/20394980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.03.001 |
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