Molecular Structure and Dimeric Organization of the Notch Extracellular Domain as Revealed by Electron Microscopy

BACKGROUND: The Notch receptor links cell fate decisions of one cell to that of the immediate cellular neighbor. In humans, malfunction of Notch signaling results in diseases and congenital disorders. Structural information is essential for gaining insight into the mechanism of the receptor as well...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Kelly, Deborah F., Lake, Robert J., Middelkoop, Teije C., Fan, Hua-Ying, Artavanis-Tsakonas, Spyros, Walz, Thomas
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866536/
https://ncbi.nlm.nih.gov/pubmed/20479883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010532
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