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Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless
The Notch receptor is the central element in an evolutionarily conserved signal transduction pathway that controls cell fates in metazoans. Receptor–ligand interactions trigger a cascade of proteolytic events that release the entire Notch intracellular domain (NICD) from the membrane, permitting its...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1887580/ https://ncbi.nlm.nih.gov/pubmed/17535912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702887104 |
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