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Molecular Structure and Dimeric Organization of the Notch Extracellular Domain as Revealed by Electron Microscopy
BACKGROUND: The Notch receptor links cell fate decisions of one cell to that of the immediate cellular neighbor. In humans, malfunction of Notch signaling results in diseases and congenital disorders. Structural information is essential for gaining insight into the mechanism of the receptor as well...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866536/ https://ncbi.nlm.nih.gov/pubmed/20479883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010532 |
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