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Biodistribution of HPMA Copolymer-Aminohexylgeldanamycin-RGDfK Conjugates for Prostate Cancer Drug Delivery

N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer-RGD (Arg-Gly-Asp) conjugates targeting the α(v)β(3) integrin present on angiogenic blood vessels and some tumor types have shown increased accumulation in solid tumors and possess properties that suggest their use for site-specific drug delivery. G...

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Autors principals: Borgman, Mark P., Aras, Omer, Geyser-Stoops, Sandra, Sausville, Edward A., Ghandehari, Hamidreza
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866446/
https://ncbi.nlm.nih.gov/pubmed/19743884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900134c
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