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Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse

RATIONALE: Several lines of evidence support a role for the endogenous opioid system in mediating behaviors associated with drug dependence. Specifically, recent findings suggest that the kappa-opioid receptor (KOR) may play a role in aspects of nicotine dependence, which contribute to relapse and c...

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Autors principals: Jackson, K. J., Carroll, Frank Ivy, Negus, S. S., Damaj, M. I.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866121/
https://ncbi.nlm.nih.gov/pubmed/20232057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1803-1
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