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Targeted Delivery of Paclitaxel to Tumor Cells: Synthesis and In Vitro Evaluation

We previously reported a novel drug delivery system, drug-linker-Phe-Phe-Arg-methylketone-(FFR-mk)-factor VIIa (fVIIa). The method utilizes tissue factor (TF), which is aberrantly and abundantly expressed on many cancer cells. The advantage of this delivery system is its ability to furnish a potent...

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Detalles Bibliográficos
Main Authors: Ndungu, John M., Lu, Yang J., Zhu, Shijun, Yang, Chao, Wang, Xu, Chen, Georgia, Shin, Dong M., Snyder, James P., Shoji, Mamoru, Sun, Aiming
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866085/
https://ncbi.nlm.nih.gov/pubmed/20302303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901763f
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