Tumor Angiogenesis Therapy Using Targeted Delivery of Paclitaxel to the Vasculature of Breast Cancer Metastases

Breast cancer aberrantly expresses tissue factor (TF) in cancer tissues and cancer vascular endothelial cells (VECs). TF plays a central role in cancer angiogenesis, growth, and metastasis and, as such, is a target for therapy and drug delivery. TF is the cognate receptor of factor VIIa (fVIIa). We...

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Detalhes bibliográficos
Publicado no:J Drug Deliv
Main Authors: Zhu, Shijun, Kisiel, Walter, Lu, Yang J., Petersen, Lars C., Ndungu, John M., Moore, Terry W., Parker, Ernest T., Sun, Aiming, Liotta, Dennis C., El-Rayes, Bassel F., Brat, Daniel J., Snyder, James P., Shoji, Mamoru
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273585/
https://ncbi.nlm.nih.gov/pubmed/25574399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/865732
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