Laddar...

Curcumin analog cytotoxicity against breast cancer cells: Exploitation of a redox-dependent mechanism

A series of novel curcumin analogs, symmetrical dienones, were previously shown to possess cytotoxic, anti-angiogenic and anti-tumor activities. Analogs 1 (EF24) and 2 (EF31) share the dienone scaffold and serve as Michael acceptors. We propose that the anticancer effects of 1 and 2 are mediated in...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Sun, Aiming, Lu, Yang J., Hu, Haipeng, Shoji, Mamoru, Liotta, Dennis C., Snyder, James P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791955/
https://ncbi.nlm.nih.gov/pubmed/19854644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.10.023
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!