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Heparanase upregulaes Th2 cytokines, ameliorating experimental autoimmune encephalitis

Heparanase is an endo–β–D-glucuronidase that cleaves heparan sulfate (HS) saccharide chains. The enzyme promotes cell adhesion, migration and invasion and plays a significant role in cancer metastasis, angiogenesis and inflammation. The present study focuses on the involvement of heparanase in autoi...

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Huvudupphovsmän: Bitan, Menachem, Weiss, Lola, Reibstein, Israel, Zeira, Michael, Fellig, Yakov, Slavin, Shimon, Zcharia, Eyal, Nagler, Arnon, Vlodavsky, Israel
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865651/
https://ncbi.nlm.nih.gov/pubmed/20399501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.03.014
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