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Heparanase upregulaes Th2 cytokines, ameliorating experimental autoimmune encephalitis
Heparanase is an endo–β–D-glucuronidase that cleaves heparan sulfate (HS) saccharide chains. The enzyme promotes cell adhesion, migration and invasion and plays a significant role in cancer metastasis, angiogenesis and inflammation. The present study focuses on the involvement of heparanase in autoi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865651/ https://ncbi.nlm.nih.gov/pubmed/20399501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.03.014 |
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