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Effects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes

BACKGROUND: Identifying developmental processes regulated by Notch1 can be addressed in part by characterizing mice with graded levels of Notch1 signaling strength. Here we examine development in embryos expressing various combinations of Notch1 mutant alleles. Mice homozygous for the hypomorphic No...

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Autors principals: Ge, Changhui, Stanley, Pamela
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865454/
https://ncbi.nlm.nih.gov/pubmed/20346184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-36
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