Biological Significance of NOTCH Signaling Strength

The evolutionarily conserved NOTCH signaling displays pleotropic functions in almost every organ system with a simple signaling axis. Different from many other signaling pathways that can be amplified via kinase cascades, NOTCH signaling does not contain any intermediate to amplify signal. Thus, NOT...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Shen, Wei, Huang, Jiaxin, Wang, Yan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033010/
https://ncbi.nlm.nih.gov/pubmed/33842479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.652273
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