Modification of Integration Site Preferences of an HIV-1-Based Vector by Expression of a Novel Synthetic Protein

HIV-1-based lentiviral vectors are a promising tool for gene therapy. However, integration of a lentiviral vector into host cell genes may lead to the development of cancer. Therefore, control of integration site selection is critical to the successful outcome of gene therapy approaches that use the...

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Detalhes bibliográficos
Main Authors: Silvers, Robert M., Smith, Johanna A., Schowalter, Michael, Litwin, Samuel, Liang, Zhihui, Geary, Kyla, Daniel, René
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865216/
https://ncbi.nlm.nih.gov/pubmed/19877879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.134
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