Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences

The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA integration. Here we report an analysis of 3,127 integration site sequences from human cells. We compared retroviral vectors derived from human immunodeficiency virus (HIV), avian sarcoma-leukosis vir...

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Main Authors: Mitchell, Rick S, Beitzel, Brett F, Schroder, Astrid R. W, Shinn, Paul, Chen, Huaming, Berry, Charles C, Ecker, Joseph R, Bushman, Frederic D
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2004
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC509299/
https://ncbi.nlm.nih.gov/pubmed/15314653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020234
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