Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences

The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA integration. Here we report an analysis of 3,127 integration site sequences from human cells. We compared retroviral vectors derived from human immunodeficiency virus (HIV), avian sarcoma-leukosis vir...

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Detalhes bibliográficos
Main Authors: Mitchell, Rick S, Beitzel, Brett F, Schroder, Astrid R. W, Shinn, Paul, Chen, Huaming, Berry, Charles C, Ecker, Joseph R, Bushman, Frederic D
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC509299/
https://ncbi.nlm.nih.gov/pubmed/15314653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020234
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