Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences

The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA integration. Here we report an analysis of 3,127 integration site sequences from human cells. We compared retroviral vectors derived from human immunodeficiency virus (HIV), avian sarcoma-leukosis vir...

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Bibliographic Details
Main Authors: Mitchell, Rick S, Beitzel, Brett F, Schroder, Astrid R. W, Shinn, Paul, Chen, Huaming, Berry, Charles C, Ecker, Joseph R, Bushman, Frederic D
Format: Artigo
Language:Inglês
Published: Public Library of Science 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC509299/
https://ncbi.nlm.nih.gov/pubmed/15314653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020234
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