A Modified Method for Determination of Lumefantrine in Human Plasma by HPLC-UV and Combination of Protein Precipitation and Solid-Phase Extraction: Application to a Pharmacokinetic Study

An HPLC-UV method was developed and validated for the determination of lumefantrine in human plasma. Lumefantrine and its internal standard halofantrine were extracted from plasma samples using protein precipitation with acetonitrile (0.2% perchloric acid) followed by solid-phase extraction with Hyp...

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Detalhes bibliográficos
Main Authors: Huang, Liusheng, Lizak, Patricia S., Jayewardene, Anura L., Marzan, Florence, Lee, Ming-Na Tina, Aweeka, Francesca T.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2010
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865164/
https://ncbi.nlm.nih.gov/pubmed/20448843
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