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Molecular Mechanisms of System Control of NF-κB Signaling by IκBα

The NF-κB family of transcription factors responds to inflammatory cytokines with rapid transcriptional activation and subsequent signal repression. Much of the system control depends on the unique characteristics of its major inhibitor, IκBα, which appears to have folding dynamics that underlie the...

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Autors principals: Ferreiro, Diego U., Komives, Elizabeth A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865148/
https://ncbi.nlm.nih.gov/pubmed/20055496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901948j
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