Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester.
Skeletal muscle degeneration associated with mitochondrial damage was found after marked depletion of glutathione produced by administration to mice of buthionine sulfoximine, an irreversible inhibitor of gamma-glutamylcysteine synthetase. No mitochondrial damage was found in heart. These studies sh...
Na minha lista:
| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1989
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911592/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.471 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|