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Glutathione metabolism in the lung: inhibition of its synthesis leads to lamellar body and mitochondrial defects.

Mice treated with buthionine sulfoximine, an inhibitor of glutathione synthesis, showed striking alterations of morphology of lung type 2 cell lamellar bodies (swelling and disintegration) and mitochondria (degeneration) and of lung capillary endothelial cells (mitochondrial swelling). These effects...

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Detalhes bibliográficos
Main Authors: Mårtensson, J, Jain, A, Frayer, W, Meister, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC297608/
https://ncbi.nlm.nih.gov/pubmed/2748585
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