Glutathione metabolism in the lung: inhibition of its synthesis leads to lamellar body and mitochondrial defects.
Mice treated with buthionine sulfoximine, an inhibitor of glutathione synthesis, showed striking alterations of morphology of lung type 2 cell lamellar bodies (swelling and disintegration) and mitochondria (degeneration) and of lung capillary endothelial cells (mitochondrial swelling). These effects...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2748585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5296 |
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