Crystallization and preliminary X-ray analysis of 6-­hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus

6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK) catalyzes the Mg(2+)-dependent transfer of pyrophosphate from ATP to 6-hydroxymethyl-7,8-­dihydropterin (HMDP), forming 6-hydroxymethyl-7,8-dihydropterin pyro­phosphate, which is a critical step in the de novo folic acid-biosynthesis pathway...

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Autores principales: Chhabra, Sandeep, Newman, Janet, Peat, Thomas S., Fernley, Ross T., Caine, Joanne, Simpson, Jamie S., Swarbrick, James D.
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2010
Materias:
Crystallization Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864696/
https://ncbi.nlm.nih.gov/pubmed/20445263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110010857
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