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Asymmetric, Organocatalytic, Three-Step Synthesis of α-Hydroxy-(E)-β,γ-Unsaturated Esters

[Image: see text] An efficient and enantiocontrolled 3-step synthesis of α-hydroxy-(E)-β,γ-unsaturated esters is reported. Enantioenriched α-selenyl aldehydes, prepared in one step by asymmetric, organocatalytic α-selenylation of aldehydes, were directly subjected to a Wittig reaction followed by al...

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Detalhes bibliográficos
Principais autores: Hess, Lindsey C., Posner, Gary H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864524/
https://ncbi.nlm.nih.gov/pubmed/20377201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100615j
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