GPR30, but not estrogen receptor-α, is crucial in the treatment of experimental autoimmune encephalomyelitis by oral ethinyl estradiol

BACKGROUND: Remission of multiple sclerosis during periods of high ovarian hormone secretion (such as pregnancy) has led to a great deal of interest in the potential for estrogens to treat autoimmune disease. Previous work has established that 17β-estradiol can inhibit onset of experimental autoimmu...

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Bibliographic Details
Main Authors: Yates, Melissa A, Li, Yuexin, Chlebeck, Peter J, Offner, Halina
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864220/
https://ncbi.nlm.nih.gov/pubmed/20403194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-11-20
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