The Protective Effect of 17β-Estradiol on Experimental Autoimmune Encephalomyelitis Is Mediated through Estrogen Receptor-α

Low-dose estrogen (E2) treatment significantly inhibits the clinical signs and histopathological lesions of experimental autoimmune encephalomyelitis (EAE), and is being used in clinical trials to treat multiple sclerosis. To assess the role of intracytoplasmic estrogen receptors in mediating suppre...

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Hauptverfasser: Polanczyk, Magdalena, Zamora, Alex, Subramanian, Sandhya, Matejuk, Agata, Hess, David L., Blankenhorn, Elizabeth P., Teuscher, Cory, Vandenbark, Arthur A., Offner, Halina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868300/
https://ncbi.nlm.nih.gov/pubmed/14507666
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