T Lymphocytes Do Not Directly Mediate the Protective Effect of Estrogen on Experimental Autoimmune Encephalomyelitis

Gender influences mediated by 17β-estradiol (E2) have been associated with susceptibility to and severity of autoimmune diseases such as diabetes, arthritis, and multiple sclerosis. In this regard, we have shown that estrogen receptor-α (Esr1) is crucial for the protective effect of 17β-estradiol (E...

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Main Authors: Polanczyk, Magdalena J., Jones, Richard E., Subramanian, Sandhya, Afentoulis, Michael, Rich, Cathleen, Zakroczymski, Melissa, Cooke, Paul, Vandenbark, Arthur A., Offner, Halina
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2004
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Original Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618702/
https://ncbi.nlm.nih.gov/pubmed/15579449
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