ロード中...
Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2
The X-ray structure at 2.0-Å resolution of the p90 ribosomal S6 kinase 2 C-terminal kinase domain revealed a C-terminal autoinhibitory αL-helix that was embedded in the kinase scaffold and determines the inactive kinase conformation. We suggest a mechanism of activation through displacement of the α...
保存先:
| 主要な著者: | , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864125/ https://ncbi.nlm.nih.gov/pubmed/18084304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1347 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|