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The Crystal Structure of the Active Form of the C-Terminal Kinase Domain of Mitogen- And Stress-Activated Protein Kinase 1

Mitogen- and stress-activated protein kinase 1 (MSK1) is a growth factor-stimulated serine/threonine kinase that is involved in gene transcription regulation and proinflammatory cytokine stimulation. MSK1 is a dual kinase possessing two non-identical protein kinase domains in one polypeptide. We pre...

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Bibliographic Details
Main Authors: Malakhova, Margarita, D'Angelo, Igor, Kim, Hong-Gyum, Kurinov, Igor, Bode, Ann M., Dong, Zigang
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897027/
https://ncbi.nlm.nih.gov/pubmed/20382163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.064
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