Structural Diversity of the Active N-Terminal Kinase Domain of p90 Ribosomal S6 Kinase 2

The p90 ribosomal protein kinase 2 (RSK2) is a highly expressed Ser/Thr kinase activated by growth factors and is involved in cancer cell proliferation and tumor promoter-induced cell transformation. RSK2 possesses two non-identical kinase domains, and the structure of its N-terminal domain (NTD), w...

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Main Authors: Malakhova, Margarita, Kurinov, Igor, Liu, Kangdong, Zheng, Duo, D'Angelo, Igor, Shim, Jung-Hyun, Steinman, Valerie, Bode, Ann M., Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779450/
https://ncbi.nlm.nih.gov/pubmed/19956600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008044
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