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Structural Diversity of the Active N-Terminal Kinase Domain of p90 Ribosomal S6 Kinase 2
The p90 ribosomal protein kinase 2 (RSK2) is a highly expressed Ser/Thr kinase activated by growth factors and is involved in cancer cell proliferation and tumor promoter-induced cell transformation. RSK2 possesses two non-identical kinase domains, and the structure of its N-terminal domain (NTD), w...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779450/ https://ncbi.nlm.nih.gov/pubmed/19956600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008044 |
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