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Characterization of the Roco Protein Family in Dictyostelium discoideum

The Roco family consists of multidomain Ras-GTPases that include LRRK2, a protein mutated in familial Parkinson's disease. The genome of the cellular slime mold Dictyostelium discoideum encodes 11 Roco proteins. To study the functions of these proteins, we systematically knocked out the roco ge...

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Détails bibliographiques
Auteurs principaux: van Egmond, Wouter N., van Haastert, Peter J. M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863948/
https://ncbi.nlm.nih.gov/pubmed/20348387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00366-09
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