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Characterization of the Roco Protein Family in Dictyostelium discoideum

The Roco family consists of multidomain Ras-GTPases that include LRRK2, a protein mutated in familial Parkinson's disease. The genome of the cellular slime mold Dictyostelium discoideum encodes 11 Roco proteins. To study the functions of these proteins, we systematically knocked out the roco ge...

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書誌詳細
主要な著者: van Egmond, Wouter N., van Haastert, Peter J. M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863948/
https://ncbi.nlm.nih.gov/pubmed/20348387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00366-09
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