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Intramolecular Activation Mechanism of the Dictyostelium LRRK2 Homolog Roco Protein GbpC

GbpC is a large multidomain protein involved in cGMP-mediated chemotaxis in the cellular slime mold Dictyostelium discoideum. GbpC belongs to the Roco family of proteins that often share a central core region, consisting of leucine-rich repeats, a Ras domain (Roc), a Cor domain, and a MAPKKKinase do...

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Detalhes bibliográficos
Main Authors: van Egmond, Wouter N., Kortholt, Arjan, Plak, Katarzyna, Bosgraaf, Leonard, Bosgraaf, Sylvia, Keizer-Gunnink, Ineke, van Haastert, Peter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662088/
https://ncbi.nlm.nih.gov/pubmed/18703517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804265200
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