Phenotypic and Functional Profile of HIV-Inhibitory CD8 T Cells Elicited by Natural Infection and Heterologous Prime/Boost Vaccination

Control of HIV-1 replication following nonsterilizing HIV-1 vaccination could be achieved by vaccine-elicited CD8(+) T-cell-mediated antiviral activity. To date, neither the functional nor the phenotypic profiles of CD8(+) T cells capable of this activity are clearly understood; consequently, little...

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Autores principales: Freel, Stephanie A., Lamoreaux, Laurie, Chattopadhyay, Pratip K., Saunders, Kevin, Zarkowsky, David, Overman, R. Glenn, Ochsenbauer, Christina, Edmonds, Tara G., Kappes, John C., Cunningham, Coleen K., Denny, Thomas N., Weinhold, Kent J., Ferrari, Guido, Haynes, Barton F., Koup, Richard A., Graham, Barney S., Roederer, Mario, Tomaras, Georgia D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863846/
https://ncbi.nlm.nih.gov/pubmed/20200250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00138-10
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