Initial HIV-1 Antigen-Specific CD8(+) T Cells in Acute HIV-1 Infection Inhibit Transmitted/Founder Virus Replication

CD8-mediated virus inhibition can be detected in HIV-1-positive subjects who naturally control virus replication. Characterizing the inhibitory function of CD8(+) T cells during acute HIV-1 infection (AHI) can elucidate the nature of the CD8(+) responses that can be rapidly elicited and that contrib...

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Autors principals: Freel, Stephanie A., Picking, Ralph A., Ferrari, Guido, Ding, Haitao, Ochsenbauer, Christina, Kappes, John C., Kirchherr, Jennifer L., Soderberg, Kelly A., Weinhold, Kent J., Cunningham, Coleen K., Denny, Thomas N., Crump, John A., Cohen, Myron S., McMichael, Andrew J., Haynes, Barton F., Tomaras, Georgia D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Cellular Response to Infection
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393529/
https://ncbi.nlm.nih.gov/pubmed/22514337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00437-12
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