Initial HIV-1 Antigen-Specific CD8(+) T Cells in Acute HIV-1 Infection Inhibit Transmitted/Founder Virus Replication

CD8-mediated virus inhibition can be detected in HIV-1-positive subjects who naturally control virus replication. Characterizing the inhibitory function of CD8(+) T cells during acute HIV-1 infection (AHI) can elucidate the nature of the CD8(+) responses that can be rapidly elicited and that contrib...

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Detalhes bibliográficos
Main Authors: Freel, Stephanie A., Picking, Ralph A., Ferrari, Guido, Ding, Haitao, Ochsenbauer, Christina, Kappes, John C., Kirchherr, Jennifer L., Soderberg, Kelly A., Weinhold, Kent J., Cunningham, Coleen K., Denny, Thomas N., Crump, John A., Cohen, Myron S., McMichael, Andrew J., Haynes, Barton F., Tomaras, Georgia D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393529/
https://ncbi.nlm.nih.gov/pubmed/22514337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00437-12
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