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Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication

CD8(+) T-lymphocytes from HIV-1 infected individuals express unidentified factors that suppress viral replication by inhibiting HIV-1 gene expression. We examined the role of epigenetics in modulating the HIV-1 suppressive factors expressed by primary CD8(+) T cells from subjects naturally controlli...

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Detalhes bibliográficos
Main Authors: Saunders, Kevin O., Freel, Stephanie A., Overman, R. Glenn, Cunningham, Coleen K., Tomaras, Georgia D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664273/
https://ncbi.nlm.nih.gov/pubmed/20594570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.06.001
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