Phenotypic and Functional Profile of HIV-Inhibitory CD8 T Cells Elicited by Natural Infection and Heterologous Prime/Boost Vaccination

Control of HIV-1 replication following nonsterilizing HIV-1 vaccination could be achieved by vaccine-elicited CD8(+) T-cell-mediated antiviral activity. To date, neither the functional nor the phenotypic profiles of CD8(+) T cells capable of this activity are clearly understood; consequently, little...

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Main Authors: Freel, Stephanie A., Lamoreaux, Laurie, Chattopadhyay, Pratip K., Saunders, Kevin, Zarkowsky, David, Overman, R. Glenn, Ochsenbauer, Christina, Edmonds, Tara G., Kappes, John C., Cunningham, Coleen K., Denny, Thomas N., Weinhold, Kent J., Ferrari, Guido, Haynes, Barton F., Koup, Richard A., Graham, Barney S., Roederer, Mario, Tomaras, Georgia D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863846/
https://ncbi.nlm.nih.gov/pubmed/20200250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00138-10
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