T-Cell Correlates of Vaccine Efficacy after a Heterologous Simian Immunodeficiency Virus Challenge

Determining the “correlates of protection” is one of the challenges in human immunodeficiency virus vaccine design. To date, T-cell-based AIDS vaccines have been evaluated with validated techniques that measure the number of CD8(+) T cells in the blood that secrete cytokines, mainly gamma interferon...

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Autori principali: Martins, Mauricio A., Wilson, Nancy A., Reed, Jason S., Ahn, Chanook D., Klimentidis, Yann C., Allison, David B., Watkins, David I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863752/
https://ncbi.nlm.nih.gov/pubmed/20164222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02365-09
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