Efficacy of Multivalent Adenovirus-Based Vaccine against Simian Immunodeficiency Virus Challenge

The prophylactic efficacies of several multivalent replication-incompetent adenovirus serotype 5 (Ad5) vaccines were examined in rhesus macaques using an intrarectal high-dose simian immunodeficiency virus SIVmac239 challenge model. Cohorts of Mamu-A*01(+)/B*17(−) Indian rhesus macaques were immuniz...

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Détails bibliographiques
Auteurs principaux: Casimiro, Danilo R., Cox, Kara, Tang, Aimin, Sykes, Kara J., Feng, Meizhen, Wang, Fubao, Bett, Andrew, Schleif, William A., Liang, Xiaoping, Flynn, Jessica, Tobery, Timothy W., Wilson, Keith, Finnefrock, Adam, Huang, Lingyi, Vitelli, Salvatore, Lin, Jing, Patel, Deepa, Davies, Mary-Ellen, Heidecker, Gwendolyn J., Freed, Daniel C., Dubey, Sheri, O'Connor, David H., Watkins, David I., Zhang, Zhi-Qiang, Shiver, John W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826028/
https://ncbi.nlm.nih.gov/pubmed/20042509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00969-09
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