Efficacy of Multivalent Adenovirus-Based Vaccine against Simian Immunodeficiency Virus Challenge

The prophylactic efficacies of several multivalent replication-incompetent adenovirus serotype 5 (Ad5) vaccines were examined in rhesus macaques using an intrarectal high-dose simian immunodeficiency virus SIVmac239 challenge model. Cohorts of Mamu-A*01(+)/B*17(−) Indian rhesus macaques were immuniz...

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Detalhes bibliográficos
Main Authors: Casimiro, Danilo R., Cox, Kara, Tang, Aimin, Sykes, Kara J., Feng, Meizhen, Wang, Fubao, Bett, Andrew, Schleif, William A., Liang, Xiaoping, Flynn, Jessica, Tobery, Timothy W., Wilson, Keith, Finnefrock, Adam, Huang, Lingyi, Vitelli, Salvatore, Lin, Jing, Patel, Deepa, Davies, Mary-Ellen, Heidecker, Gwendolyn J., Freed, Daniel C., Dubey, Sheri, O'Connor, David H., Watkins, David I., Zhang, Zhi-Qiang, Shiver, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826028/
https://ncbi.nlm.nih.gov/pubmed/20042509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00969-09
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