Efficacy of Multivalent Adenovirus-Based Vaccine against Simian Immunodeficiency Virus Challenge

The prophylactic efficacies of several multivalent replication-incompetent adenovirus serotype 5 (Ad5) vaccines were examined in rhesus macaques using an intrarectal high-dose simian immunodeficiency virus SIVmac239 challenge model. Cohorts of Mamu-A*01(+)/B*17(−) Indian rhesus macaques were immuniz...

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Main Authors: Casimiro, Danilo R., Cox, Kara, Tang, Aimin, Sykes, Kara J., Feng, Meizhen, Wang, Fubao, Bett, Andrew, Schleif, William A., Liang, Xiaoping, Flynn, Jessica, Tobery, Timothy W., Wilson, Keith, Finnefrock, Adam, Huang, Lingyi, Vitelli, Salvatore, Lin, Jing, Patel, Deepa, Davies, Mary-Ellen, Heidecker, Gwendolyn J., Freed, Daniel C., Dubey, Sheri, O'Connor, David H., Watkins, David I., Zhang, Zhi-Qiang, Shiver, John W.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826028/
https://ncbi.nlm.nih.gov/pubmed/20042509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00969-09
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