Human AlkB Homolog ABH8 Is a tRNA Methyltransferase Required for Wobble Uridine Modification and DNA Damage Survival

tRNA nucleosides are extensively modified to ensure their proper function in translation. However, many of the enzymes responsible for tRNA modifications in mammals await identification. Here, we show that human AlkB homolog 8 (ABH8) catalyzes tRNA methylation to generate 5-methylcarboxymethyl uridi...

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Xehetasun bibliografikoak
Egile Nagusiak: Fu, Dragony, Brophy, Jennifer A. N., Chan, Clement T. Y., Atmore, Kyle A., Begley, Ulrike, Paules, Richard S., Dedon, Peter C., Begley, Thomas J., Samson, Leona D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
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Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863699/
https://ncbi.nlm.nih.gov/pubmed/20308323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01604-09
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