Identification of katG Mutations Associated with High-Level Isoniazid Resistance in Mycobacterium tuberculosis

Isoniazid (INH) is an effective first-line antituberculosis drug. KatG, a catalase-peroxidase, converts INH to an active form in Mycobacterium tuberculosis, and katG mutations are major causes of INH resistance. In the present study, we sequenced katG of 108 INH-resistant M. tuberculosis clinical is...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ando, Hiroki, Kondo, Yuji, Suetake, Toshinori, Toyota, Emiko, Kato, Seiya, Mori, Toru, Kirikae, Teruo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863633/
https://ncbi.nlm.nih.gov/pubmed/20211896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01691-09
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars