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Increased Tolerance to Artemisinin in Plasmodium falciparum Is Mediated by a Quiescence Mechanism

Artemisinin (ART)-based combination therapies (ACTs) are the first-line drugs—and often the last treatments—that can effectively cure Plasmodium falciparum infections. Unfortunately, the decreased clinical efficacy of artesunate, one of the major ART derivatives, was recently reported along the Thai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Witkowski, Benoit, Lelièvre, Joel, López Barragán, María José, Laurent, Victor, Su, Xin-zhuan, Berry, Antoine, Benoit-Vical, Françoise
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863624/
https://ncbi.nlm.nih.gov/pubmed/20160056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01636-09
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