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Regulation of Bile Acid Synthesis by Fat-soluble Vitamins A and D
Bile acids are required for proper absorption of dietary lipids, including fat-soluble vitamins. Here, we show that the dietary vitamins A and D inhibit bile acid synthesis by repressing hepatic expression of the rate-limiting enzyme CYP7A1. Receptors for vitamin A and D induced expression of Fgf15,...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863217/ https://ncbi.nlm.nih.gov/pubmed/20233723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116004 |
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